Disorders of the Sleep-Wake Cycle in Blindness

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Disorders of the sleep-wake cycle in blindness.

BACKGROUND Alteration of the intensity of light reaching the pineal gland through the visual pathway affects the sleepwake cycle in humans. OBJECTIVE To determine the prevalence, types and severity of sleep-wake disorders in the blind and their relation to the degree and cause of blindness. METHODS One hundred and seventy consecutive blind patients were included in the study. The patients w...

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Prevalence of sleep/wake disorders in persons with blindness.

Blind individuals are not only handicapped by their loss of vision, but are also affected because the loss of sight may have a secondary impact on functioning of their biological clock. The objective of the present study was to determine the impact of visual loss on sleep/wake disorders. A prospective 48-item questionnaire survey was distributed to blind individuals through the French Associati...

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Effects of bilateral lesion of the locus coeruleus on the sleep-wake cycle in the rat

Introduction: Noradrenergic cells in LC participate in the process of cortical activation and behavioral arousal. The evidence suggests that locus ceoruleus (LC) plays an important role in the sleep-wake cycle. The aim of this study was stereological estimation of cavity caused by lesion and assessment of sleep stages after bilateral lesion of the LC. Materials and Methods: Male Wistar rats we...

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Neurochemically distinct systems interact regulating sleep and wakefulness. Wakefulness is promoted by aminergic, acetylcholinergic brainstem and hypothalamic systems. Each of these arousal systems supports wakefulness and coordinated activity is required for alertness and EEG activation. Neurons in the pons and preoptic area control rapid eye movement and non-rapid eye movement sleep. Mutual i...

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ژورنال

عنوان ژورنال: West African Journal of Medicine

سال: 2011

ISSN: 0189-160X

DOI: 10.4314/wajm.v29i3.68214